I have found no indication in the scientific literature of particular
kidney toxicity with trenbolone. I know of a number of users, at doses of typically rHGH Guide 50 mg/day, who have experienced no problems. There are however anecdotal claims of kidney problems. It seems to me, however, rHGH Guide that this is occurring only with athletes stacking an incredible amount of drugs, and how the blame can fairly be laid at trenbolone rHGH Guide (actually at Parabolan, not trenbolone acetate) is not clear.
How should I take this medicine?
Tadalafil is currently undergoing clinical trials for the treatment of pulmonary hypertension. The clinical trials are based on tadalafil's inhibitiong of PDE5. It is hoped that by inhibiting this enzyme, tadalafil will prove
effective in opening up blood vessels in the lungs, lowering pulmonary arterial resistance and pressure, and thus reducing the workload of rHGH Guide the right ventricle of the heart.
Most athletes inject Parabolan at least twice a week; some bodybuilders rHGH Guide inject 1-2 ampules per day during the last three to four weeks be-fore a competition. Normally a dosage of 228 mg/week is used, corresponding rHGH Guide to a weekly amount of three ampules. It is our experience that good results can be achieved by injecting a 76 mg ampule every 2-3 days. rHGH Guide Parabolan combined with Winstrol Depot works especially well and gives the athlete a distinct gain in solid and high quality muscles together with an enormous strength gain.
A very effective stack is 76 mg Parabolan every 2 days combined with 50 mg Winstrol every 2 days. Athletes who are interested in rHGH Guide a fast mass gain often also use 30 mg Dianabol/day while those who are more interested in quality and strength like to add 25 mg+ Oxandrolone/ rHGH Guide day. Probably the most effective Parabolan combination consists of 228 mg Parabolan/week, rHGH Guide 200 mg Winstrol Depot/week, and 40-50 mg Oral-Turinabol/day and usually results in rHGH Guide a drastic gain in high quality muscle mass together with a gigantic strength gain. Parabolan also seems rHGH Guide to bring extraordinarily good results when used in combination with growth hormones.
It is also relevant to note that muscle repair and growth begins
in the hours and days following heavy exercise. It is doubtful that the use of insulin just prior to a workout will have any anabolic effects over and rHGH Guide above natural processes, at this time. However, use of insulin prior to a workout will certainly expose rHGH Guide you to much greater risk of serious harm. If you believe it is beneficial to have a higher insulin rHGH Guide blood level during workouts, use the natural method outlined here.
Omeprazole rHGH Guide can increase the plasma concentrations and the elimination half-life of diazepam, presumably due to rHGH Guide inhibition of the hepatic metabolism of diazepam. Although the pharmacodynamics of this interaction are not clear, it is recommended that patients receiving omeprazole
and diazepam concomitantly should be monitored for enhanced diazepam response.
Testosterone cypionate is rHGH Guide a long acting ester of testosterone which is increasingly difficult to find.Before the scheduling of anabolics in the rHGH Guide U.S., this was the most common form of testosterone available to athletes. Cyp had gained a reputation as being slightly stronger than enanthate rHGH Guide and became the testosterone of choice for many. Now that anabolics are controlled, this is an almost impossible find. In general, the only rHGH Guide versions you\'ll find on the black market are Sten from Mexico, which contains 75mg cyp with 25mg propionate along with some DHEA, and Testex from Leo in Spain which contains 250mg cypionate
is a light resistant ampule. All versions of Upjohn and Steris in multi-dose vials should be looked rHGH Guide at with extreme caution as they are very difficult to get on the black market. Counterfeits are quite easy to obtain. Real Steris products have rHGH Guide the inking STAMPED into the box and the labels cannot be removed from the bottle. Any variation of that is definitely rHGH Guide counterfeit. A running dosage of test cypionate is generally in the range of 200-600mg per week. When this was available rHGH Guide for $10.00 per10ml bottle, many users would take a whopping 2000mg per week. This kind of dosage rHGH Guide however, is unsafe, generally not needed and in today's day and age too costly.
Testoviron Enanthate: 250 mg/ml 1 cc/amp.
Testoviron depot is a long acting injectable testosterone that is widely used amongst rHGH Guide athletes. It is currently the most popular testosterone ester available to athletes. Unlike cypionate, enanthate is manufactured by various companies rHGH Guide all over the world. Ampules of Testoviron depot from Schering are probably the most popular although many others rHGH Guide exist. Enanthate is a long acting testosterone similar to cypionate. Injections of Testoviron depot rHGH Guide are taken once weekly, with a dosage of 200-600mg being most common for athletes. It has very strong anabolic effects as well rHGH Guide as strong androgenic side effects. Gynocomastia and water retention are the most common side effects and should be watched for. Being
an injectable testosterone, liver values are generally not elevated much by this product. rHGH Guide It only needs to be administered once every 7 days as opposed to cypionate's weekly injections. This yields rHGH Guide greater convenience and cost effectiveness. Effective dosages of Testoviron depot range from 1 to 3 ccs every 10 days.
Release rHGH Guide Date: 1970
Although Sustanon remains active in the body for approximately three weeks, rHGH Guide injections are taken at least every 10 days. An effective dosage ranges from 250mg (one ampule) every 10 days, to 1000mg (four ampules) weekly. Some athletes do use more extreme dosages, but this is really not a recommended practice. When the dosage
rises above 750-1000mg per week, increased of Sustanon side effects will no doubt be outweighing additional An benefits. rHGH Guide Basically you will receive a poor return on your investment, which with Sustanon can be substantial. Instead of taking unnecessarily rHGH Guide large amounts, athletes interested in rapid size and strength will usually opt to addition another compound. For this purpose we rHGH Guide find that stacks extremely well with the potent orals Anadrol 50 (oxymetholone) and Dianabol (methandrostenolone). On rHGH Guide the other hand, Sustanon may work better with trenbolone or Winstrol (stanozolol) if the athlete were seeking to maintain a harder, more defined look to his physique.
Nitrates are also found in illicit
drugs such as amyl nitrate or nitrite (\"poppers\"). If you are not sure if any of your medicines contain nitrates, rHGH Guide or if you do not understand what nitrates are, ask your doctor or pharmacist. If rHGH Guide you take VIAGRA with any nitrate medicine or illicit drug containing nitrates, your blood pressure could suddenly drop rHGH Guide to an unsafe level. You could get dizzy, faint, or even have a heart attack or stroke.
As of now the main source of trenbolone is rHGH Guide from implants for cattle being converted into an injectable or transdermal compound, from powder, and of course Underground Labs. "Home rHGH Guide brewing" powder or cattle implants seems to be the preferred method of obtaining injectable trenbolone
acetate, because the user would have much more control over the potency and sterility of the drug. Trenbolone is much more expensive rHGH Guide than other anabolic steroids ranging from 15 U.S dollars per gram of powder or 150 U.S for a rHGH Guide single 10 ml bottle. The cost of trenbolone should not matter, it is worth every penny.
For many, the increased aggression found from increased testosterone levels is often a bonus in the rHGH Guide weight room as well as on the playing field. Let´s not get started on its benefits in the bedroom!
Now that the properties of trenbolone acetate have been explained we can better understand how
to use it in order to maximize its advantages. Evidence suggests that trenbolone when stacked with estrogen promotes more weight gain rHGH Guide that trenbolone alone, now I´m not telling you to go pop some birth control with rHGH Guide your trenbolone but the addition of aromatizing orals such as dianabol and a long estered testosterone such as cypionate or enanthate would produce rHGH Guide great gains in a bulking cycle. For a cutting cycle trenbolone is the best choice you have; rHGH Guide trenbolones powerful effect on nutrient shuttling allows a user to restrict calories rHGH Guide and remain in a state of positive nitrogen balance (remember what that means?). The cortisol reducing effect and binding to the glucocorticoid receptor will greatly
reduce the catabolic effects of harsh dieting and excessive amounts of cardio& not to mention that trenbolone itself may burn fat (due to it´s rHGH Guide strong AR-binding). A good choice to stack with tren in a cutting cycle is Winstrol. Winstrol has rHGH Guide a low binding affinity to the AR and thus will act in your body in vastly different ways than the Tren (i.e. in non-receptor mediated action). rHGH Guide In addition, Winstrol is a DHT-based drug and Tren is a 19-nor& throw in some Testosterone (prop), and rHGH Guide you´ll have a cutting cycle which takes advantage of all 3 major families of Anabolic Steroids (Testosterone, 19-nor, and DHT), as well as vastly different AR-binding affinities and mechanisms of action.
Common uses and directions for Anavar, oxandrolone.
The use of these STH rHGH Guide somatotropic hormone compounds offers the athlete three performance-enhancing effects. STH (somatotropic rHGH Guide hormone) has a strong anabolic effect and causes an increased protein synthesis which manifests rHGH Guide itself in a muscular hypertrophy (enlargement of muscle cells) and in a muscular hyperplasia (increase of muscle cells.) The latter is very interesting since this increase cannot
be obtained by the intake of steroids. This is probably also the reason why STH is called the strongest anabolic hormone. The second rHGH Guide effect of STH is its pronounced influence on the burning of fat. It turns more body fat into energy leading rHGH Guide to a drastic reduction in fat or allowing the athlete to increase his caloric intake. Third, and often overlooked, is the fact that STH strengthens rHGH Guide the connective tissue, tendons, and cartilages which could be one of the main reasons for the significant increase rHGH Guide in strength experienced by many athletes. Several bodybuilders and powerlifters report that through the simultaneous intake with steroids STH protects the athlete from injuries while inereasing his strength.
Irreversible hoarsening of the voice has been seen rHGH Guide in some women from very few tablets of Danabol / Dianabol: one per day for a few weeks. For this reason, in rHGH Guide the 1960s doctors decided to end what had been a fairly common practice of prescribing this rHGH Guide drug at one tab per day to women as a "tonic". It is not a good choice for the woman who chooses to use anabolic steroids. rHGH Guide
Its growth promoting effect also seems to strengthen connective tissues, cartilage and tendons. This effect should reduce rHGH Guide the susceptibility to injury (due to heavy weight training), and increase lifting ability (strength). HGH is also a safe drug for the "piss-test".
Although its use is banned by athletic committees, there is no reliable detection method. This makes clear its attraction to (among rHGH Guide others) professional bodybuilders, strength athletes and Olympic competitors, who are able to use this drug straight through a competition. There rHGH Guide is talk however that a reliable test for the exogenous administration of growth hormone has been developed, rHGH Guide and is close to being implemented. Until this happens, growth hormone will remain a highly sought after drug for the tested athlete.
Where can I keep my medicine?
Although it does not turn out to be 100% effective for everyone, it does seem to exhibit some level of effectiveness for the majority. It
works so well for some bodybuilders they can take drugs like Anadrol right up to a contest as long as they stack rHGH Guide it with Nolvadex C&K. It would seem wise to take this drug in conjunction with any steroid cycle. Most reported a dosage of rHGH Guide 10 mg to 20 mg daily got the job done. Availability of Nolvadex C&K has been fair on the black market.
Realistically, every cycle should contain testosterone. Go back and read that rHGH Guide sentence again. A beginners´ dose of testosterone (i.e. someone on their first or second cycle of AAS) would be in rHGH Guide the 250-500mgs range. Though, realistically, I wouldn´t recommend much less than 400mgs of test per cycle for anybody,
beginner or not. And guess what? The more you use the more results you get. And frequently, the more side effects too (3).
Since Restandol (Andriol) is quickly eliminated by the body it should also be considered for use before competitions rHGH Guide requiring doping tests. Women should avoid Restandol (Andriol) since the androgenic component common with testosterone rHGH Guide is also strongly developed in this compound. Restandol (Andriol) intake can occasionally rHGH Guide lead to high blood pressure, retention of fluids, acne, sexual over stimulation, and, in women, the well known virilization rHGH Guide symptoms.
Common uses and directions for Propecia
Stanol, brand name for stanozolol is one of the
most popular steroids. It is a derivative of dihydrotestosterone, much milder in effect except for the androgenic side effects associated rHGH Guide with it. It is shown to exhibit a great tendency to produce muscle growth with a milder effect than Dianabol, however as said before the water retention rHGH Guide and the androgenic effects are not a concern. It is not capable of converting into estrogen rHGH Guide so any sensitive individuals this drug is a great way to go since gyno is no problem. rHGH Guide The typical side effects can include nausea, acne, excitation or increased aggressiveness, chills, hypertension, increase in libido. Since estrogen is the culprit of producing water retention this steroid is capable of producing lean, quality
look to the physique with no fear of excess poundage except for muscle growth. This is why it makes this a favorable rHGH Guide drug for precontest or to gain a ripped look especially if stacked with a non-aromatizing rHGH Guide or milder aromatizing drugs such as Halotestin, Primobolan, Deca or Equipose.
For men is 25-150 mg every or every other day, for women 20-50 mg every or every other rHGH Guide day, length of use should be kept to 5 –12 weeks.
Enhanced sexual performance
As touched on previously, getting the right dosage of DNP is rather easy to do although the importance rHGH Guide of proper dosage cannot be overstated. It is far better for one to err on the side of too little rather than too much,
certainly in the case of the novice who does not know if they are allergic to the substance. As stated before, the commonly rHGH Guide used dosage by bodybuilders and other reasonably lean persons is 3-5mg/kg of bodyweight. This would mean rHGH Guide that a 100-kilogram bodybuilder would use anywhere from 300-500mg per day. Experienced users commonly are found using up rHGH Guide to 800mg/day relatively safely, and beginners sometimes find that they enjoy 3-5 rHGH Guide pounds of fat loss per week with as little as 200mg/day. Dosing is highly individualized rHGH Guide and most generalizations tend to collapse quite quickly; as a result, none will be attempted. Start on the low end of the scale and see how you react. It is not recommended to take more than
300mg at any one time; a larger man taking 600mg per day should divide the dose into a 5:00PM portion and another portion taken rHGH Guide approximately 30 minutes before bedtime. Someone taking 300mg/day could easily take one dose in the evening. rHGH Guide The typical cycling program is to do 7 or 8 days on, followed by 7 or 8 off; this should not decrease thyroid output dramatically and makes use of T3 rHGH Guide (triiodothyronine, brand name Cytomel) unnecessary in most cases. T4-T3 conversion does rHGH Guide decrease dramatically in the liver due to excessive heat; this begins within 24 rHGH Guide hours of the first dose. However, there is usually adequate active thyroid hormone to make it through 8 days of using it while maintaining elevated body
temperature. After approximately 3-5 days, the user may find themselves with a waking temperature that is rHGH Guide no longer elevated, even though they are still using DNP. This is due to the decrease in rHGH Guide T3 and may signal the necessity of either the use of exogenous T3 in subsequent cycles or shorter rHGH Guide cycles of the drug. In addition, the schedule given works nicely because the user is able to rHGH Guide enjoy the anabolic rebound effect on a relatively regular basis. Also, longer cycles might leave rHGH Guide the muscle fibers in a state of relative dehydration and "starved" of ATP rHGH Guide for too long; both of these readily contribute to catabolism.
Propecia is for men only. Women who are or may
potentially be pregnant must not use Propecia because of the risk that the finasteride rHGH Guide may cause a specific kind of birth defect. Likewise, women should avoid handling tablets that are crushed or broken. Propecia tablets rHGH Guide are coated to prevent contact with the active ingredient during normal handling.
Individuals between the ages of 18 rHGH Guide and 75.
Type of insulin: short acting insulin preparations are considerably safer than long acting preparations because with short acting types, it is much easier to avoid hypoglycemia with adequate food intake.
With the non-medical use of longer acting insulin preparations, a person is at real risk of experiencing hypoglycemia late in the day, particularly rHGH Guide in between meals, during or after exercise and when asleep. Regardless of this advice, rHGH Guide some people are in reality using a mixture of short and long acting insulin preparations rHGH Guide and exposing themselves to unnecessary increased risk.
This is correctly referred to as rHGH Guide "Fina"; Finaject is the acetate form of trenbolone. It was produced in a short acting ester (acetate), so its effect lasts only a short rHGH Guide time and frequent administration is necessary. Finaject was an injectable steroid of veterinary medicine, which was extremely popular in bodybuilding
and powerlifting during the 1980's. Trenbolone Acetate is a steroid having the advantages of undergoing no adverse metabolism, rHGH Guide not being affected by aromatase or 5alpha-reductase; of being very potent Class I steroid rHGH Guide binding well to the androgen receptor; and having a short half life, probably no more than a day or two though I don't believe this rHGH Guide has been measured. Fifty milligrams per day is a good dosing for someone on his first cycle or someone who is as yet less than, rHGH Guide say, 20 pounds over his natural limit; while 100 mg/day may be preferred by the more rHGH Guide advanced user who has already gained more than this. These doses are assuming that trenbolone is the only Class I steroid being use. There
really is no need to stack another - testosterone being the only sensible exception - but rHGH Guide if another is stacked then the amount of trenbolone may be reduced accordingly.
Testosteron 10 mg/ml; Sopharma BG
Trenbolone also has a very strong binding affinity to the androgen receptor (A.R), binding much rHGH Guide more strongly than testosterone. This is important, because the stronger a steroid binds to the androgen receptor rHGH Guide the better that steroid works at activating A.R dependant mechanisms of muscle growth. There is also strong supporting evidence that compounds which bind very tightly to the androgen receptor also aid in fat loss. Think as the receptors as locks
and androgens as different keys, with some keys (androgens) opening (binding) the locks (receptors) rHGH Guide much better than others. This is not to say that AR-binding is the final word on a steroid´s effectiveness. Anadrol doesn´t have any rHGH Guide measurable binding to the AR& and we all know how potent Anadrol is for mass-building.
Testosterone propionate after rHGH Guide Testosterone Cypionate and Testosterone Enanthate, is the third injectable testosterone ester that needs to be described in detail. This rHGH Guide makes sense because, unlike cypionate and enanthate, both of which are widely used and well spread in Europe. The bodybuilder will now certainly ask the question of why the characteristics of an apparently
rarely used substance are described in detail. At a first look this might seem a little rHGH Guide unusual but when looking at this substance more closely, there are several reasons that become clear. Testosterone propionate is used on rHGH Guide so few occasions in weight lifting, power lifting, and body building not because it is ineffective. On the contrary, rHGH Guide most do not know about propionate and its application potential. One acts according to the mottos "what you don't know won't rHGH Guide hurt you" and "If others don't use, it can't be any good." We do not want to go this far and call propionate the most effective testosterone ester, however, in certain applications it is superior to enanthate, cypionate,
and also undecanoate because it has characteristics, which the common testosterones do not have.
Excess conversion to estrogen rHGH Guide is also undesirable since it contributes to inhibition of the hypothalamic/pituitary/testicular axis (HPTA), can cause or aggravate rHGH Guide gynecomastia, can cause bloating, and can give unfavorable fat pattern distribution. This conversion can be somewhat rHGH Guide reduced by use of aromatase inhibitors such as Cytadren, and/or the effects of the estradiol produced may be blocked in many rHGH Guide tissues, including the hypothalamus and breast tissue, by Clomid.
We also discussed that certain steroids may indeed stimulate and act at the height of the progesterone receptor including
nandrolone and Norethandrolone. These hormones are also altered by it inducing a decrease in libido and a sense of lethargy and such, and eventhough rHGH Guide they aromatize in lesser rates than some other steroids, they show an equal capability to cause estrogenic rHGH Guide side-effects, particularly when stacked with other aromatizable compounds. Now there rHGH Guide is evidence that Winny does indeed bind to the progesterone receptor1 and its users do not indicate rHGH Guide the normal characteristics of progesterone stimulation, which bodes well for these anti-progestagenic rHGH Guide properties. There is also some clinical data that it does aid in symptoms that require progesterone suppression2. Much in the way danazol
was also successfully used. The one thing we shouldn't lose sight of however is in what rate it binds to the progesterone reception. rHGH Guide There is no data on this. For all we know it couldn't bind strong enough to compete with nandrolone or norethandrolone. So rHGH Guide its not wise to state that Winny is an anti-progestagin per se, but it does make Winny a good match for these products in stacks in rHGH Guide any case.
Androlan (o.c.) 50, 100 mg/ml; Lannett U.S.
Organ health and integrity
Side effects that may occur while rHGH Guide taking this medicine include a change in sexual function or breast enlargement. If they continue or are bothersome, check with your doctor. Contact your doctor immediately
if you experience the following side effects or symptoms of toxicity: skin rash or swelling of lips. rHGH Guide
Consider giving this paper to the person who is going to be with you when you use insulin, so they are aware of the rHGH Guide things to look out for and what to do if you should experience a hypoglycemic reaction. The following instructions rHGH Guide are for a peer observer or other person who may find you experiencing difficulty as a result of overdosing on insulin or any rHGH Guide other drug or combination of drugs.
Halotestex (fluoxymesterone) is an oral derivative of the rHGH Guide male hormone testosterone. Unlike testosterone, halotestex does not convert to estrogen. Therefore, estrogen-related
side effects such as fat deposition, water retention, and gynecomastia do not occur. rHGH Guide Halotestex has powerful androgenic properties. It is particularly noted for increased strength without significant additional weight gain. Side rHGH Guide effects include aggression, oily skin, and virilization. Halotestex is considered to be very toxic to the liver, rHGH Guide and thus must be used with caution and for short durations only.
In addition to this, there is evidence rHGH Guide that suggests that Viagra may work to amplify the "pump" response during training. The pump is thought to happen when contracting muscle fibers signal local vascular relaxation (increasing the blood flow to the working muscles). According to KS
Lau and coworkers, NO generated by neuronal NO synthase in contracting skeletal muscle fibers may regulate vascular rHGH Guide relaxation via a cGMP-mediated pathway. Since the mechanism of action for Viagra is rHGH Guide amplification of the cGMP pathway, there is ample reason to believe that the drug may indeed affect the blood rHGH Guide flow and pump to the muscle, and therefore indirectly aid in the hypertrophy response.
No. With rHGH Guide KAMAGRA, you must be sexually aroused to get an erection. If you take KAMAGRA and are not sexually stimulated, nothing will happen–you won't get an erection just by
taking the pill. KAMAGRA is not a hormone. It is not an aphrodisiac. It's a prescription medication rHGH Guide that can improve the erectile function of most men with erection problems.
(17beta-Hydroxyestra-4,9,11-trien-3-one) rHGH Guide (Trenbolone Base + Acetate Ester)
Tadalafil is a drug used to treat rHGH Guide male erectile dysfunction (impotence). It was developed by the biotechnology firm ICOS and marketed worldwide by Eli Lilly and rHGH Guide Company under the brand name Cialis.
Athletes who are more advanced or weigh more than 220 pounds can increase the dosage to 150 mg/day rHGH Guide in the third week. This dosage, however, should not be taken for periods longer than two to three weeks.
thing to stack it with is testosterone of course. Its most easily bound to SHBG and albumin, and deactivated for up to 98%. Since the DHT rHGH Guide can compete for these structures with higher affinity it would naturally lead to a higher yield of whatever testosterone product you stacked it with. rHGH Guide Since DHT levels are notably higher now there is also more stimulation of the androgen receptor causing more strength gains, and because of its rHGH Guide affinity for aromatase the overall estrogen level decreases as well. This has as a result that gains rHGH Guide are leaner, and once again the overall testosterone yield is increased as less I converted at the aromatase enzyme.
Testosterone suspension is an injectable preparation
containing unesterfied testosterone in a water base. Among athletes, testosterone suspension has a reputation of being an extremely rHGH Guide potent injectable, often ranked highest among the testosterones. Very fast acting, testosterone rHGH Guide suspension will sustain elevated testosterone levels for only 2-3 days. Athletes will most commonly inject "suspension" rHGH Guide daily, at a dosage of 50-100 mg.
Testosterone occurs naturally in both the male and female body, rHGH Guide as insofar as drug testing for it, typical tests don´t work (i.e. testing for metabolites). Testosterone rHGH Guide can be tested for on a testosterone/epitestosterone ratio, a failing result usually being anything over 6 to 1, but there are
other more effective tests currently in use as well as being developed by the usual party-poopers in the IOC and FDA. Noteworthy is that if you are rHGH Guide using low doses of this drug and stop taking it 36-48 hours before a Test/EpiTest analysis, you can still pass!
Clenbuterol is used post cycle to aid in recovery. It allows people to keep eating large amounts rHGH Guide of foot without adding excess adipose tissue (fat).
Like all medicines, rHGH Guide Cialis ® can have side effects. These effects are normally mild to moderate in nature. The most common undesirable rHGH Guide effects are headache and indigestion. Less commonly reported side effects are back pain, muscle aches, nasal congestion, facial flushing
and dizziness. Uncommon effects are swelling of the eyelids, eye pain and red eyes. If you have any of these side rHGH Guide effects and they are troublesome, sever, or do not go away, tell your doctor.
Winstrol (stanozolol) is a relatively low androgenic rHGH Guide steroid which does not seem to aromatize. Winstrol can be toxic to the liver in excessive rHGH Guide dosages. Winstrol is a popular all purpose steroid; many stack with Primobolan or Parabolan for cutting, others stack rHGH Guide it with testosterone for size and strength gains. Women often use winstrol but occasionally it can cause virilization, even at low dosages. Winstrol gives a solid muscle gain and an overproportionally strong strength, which usually remains after
use of Winstrol is discontinued.
Being a testosterone product, all the standard rHGH Guide androgenic side effects are also to be expected. Oily skin, acne, aggressiveness, facial/body rHGH Guide hair growth and male pattern baldness are all possible. Older or more sensitive individuals might therefore choose to avoid rHGH Guide testosterone products, and look toward milder anabolics like Deca-Durabolin or Equipoise which produce fewer side effects. Others rHGH Guide may opt to add the drug Proscar/Propecia which will minimize the conversion of testosterone into rHGH Guide DHT (dihydrotestosterone). With blood levels of this metabolite notably reduced, the impact of related side effects should also be reduced. With strong bulking drugs however,
the user will generally expect to incur strong side effects and will often just tolerate them. Most athletes really do not find the rHGH Guide testosterones all that uncomfortable (especially in the face of the end result), rHGH Guide as can be seen with the great popularity of such compounds.
Danabol / Dianabol can be combined rHGH Guide with, for instance Oxandrolone or Winstrol tablets as well as with injectable steroids such rHGH Guide as Sustanon or Testosterone enanthate.
Begginer can to gain 20 to 30 pounds of mass less than into 6 weeks,with only one or two tablets daily. Reason is high water retention which can have both,positive
and negative side.Positive is a higher level of strenght and power becouse lot of water in muscles and joints which can prevent injury rHGH Guide too.Negative can be lost of body definition and high blood pressure.
Trenbolone increases nitrogen retention in muscle tissue. This rHGH Guide is of note because nitrogen retention is a strong indicator of how anabolic a substance rHGH Guide is. However, trenbolone´s incredible mass building effects do not end there. Trenbolone has the ability to bind with the receptors of the anti-anabolic rHGH Guide (muscle destroying) glucocorticoid hormones. This may also has the effect of inhibiting the catabolic (muscle destroying) hormone cortisol.
CIALIS ® 20mg / TADALAFIL
Important information about Rohypnol
Usually 50-100 mg will suffice, the lower end is preferred for maximal results rHGH Guide since estrogen plays a key role in gains, but those more worried about estrogen should opt for a higher rHGH Guide dose. For those worried about androgenic side-effects (hair loss, prostate hypertrophy, rHGH Guide deepening of voice), one can utilize the hair loss treatment finasteride. This blocks the 5-alpha-reductase enzyme and stops the conversion rHGH Guide of testosterone to the more androgenic compound DHT. I'm not a big fan of this, because DHT reduces estrogenic bloat, increases free levels of testosterone and is a very potent androgen that is 3-4 times stronger than testosterone. Those
worried about hair loss however, may want to opt for arimidex as their anti-aromatase, since Proviron rHGH Guide is a form of DHT after all.
Winny is mostly quite well-tolerated in men. Cramps, headaches, elevated blood pressure and rHGH Guide cholesterol levels and liver damage are noted, but on a not so-frequent basis. Standard virilization symptoms associated with the stimulating of the rHGH Guide androgen receptor, however, are a problem. Acne, prostate hypertrophy and an aggravation of male pattern baldness rHGH Guide can occur, so use by women has to be discouraged.
The principle drawback to Anadrol 50 (Oxydrol) rHGH Guide is that it is a 17alpha alkylated compound. Although this design gives it the ability to withstand oral
administration, it can be very stressful to the liver. Anadrol (Oxydrol) is particularly dubious rHGH Guide because we require such a high milligram amount per dosage. The difference is great when comparing it to other oral steroids like Dianabol rHGH Guide or Winstrol, which have the same chemical alteration. Since they have a slightly higher affinity rHGH Guide for the androgen receptor, they are effective in much smaller doses. Anadrol 50 has a lower affinity, which rHGH Guide may be why we have a 50mg tablet dosage. When looking at the medical requirements, the recommended dosage for all ages has been rHGH Guide 1 - 5 mg/kg of body weight. This would give a 220lb person a dosage as high as 10 Anadrol 50 tablets (500mg) per day. There should be little
wonder why when liver cancer has been linked to steroid use, Anadrol 50 (Oxydrol) is generally rHGH Guide the culprit. Athletes actually never need such a high dosage and will take in the range of only 1-3 rHGH Guide tablets per day. Many happily find that one tablet is all they need for exceptional results, and avoid higher rHGH Guide amounts. Cautious users will also limit the intake of this compound to no longer than 4-6 weeks and have their liver rHGH Guide enzymes checked regularly with a doctor. Kidney functions may also need to be looked after during longer use, as water retention/high blood pressure can rHGH Guide take a toll on the body. Before starting a cycle, one should know to give Anadrol 50 the respect it is due. It is a very powerful drug,
but not always a friendly one.
According to studies in the New England Journal of Medicine GH use will:
Shed Bodyfat, Increase Muscle Tone; Boost your Energy, Strength, and Endurance
Reduce Wrinkles and Create Tighter, Smoother Skin; Help you Sleep Better, Improve
Sex Drive and Performance, Improve Immune and Heart Function, Bone Density, Healing
Time and Cholesterol, Improve Brain Function, Memory and Mental Focus
Wow! Sure sounds like a wonder drug to me! Yeah right, anyway here is some real world
information for bodybuilders. Somatropin (rHGH) is produced by the pituitary gland
and is responsible in adolescence for growth of tissues, protein deposition, and the
breakdown of sub-q fat stores. As we age, growth hormone levels decrease but still
remain active in the body, releasing in cycles during the day. Synthetic growth hormone
used exogenously by bodybuilders is a 191 chain sequence of amino acids that replicates
the bodies natural production of growth hormone.
Growth hormone has been in use by bodybuilders since the early 1980’s, though at
this time, HGH was being extracted from the pituitary glands of cadavers and had enormous
side effects, most prominently Creutzfeldt Jacob disease. This is a rare and fatal
brain disease, it need not be discussed here since it is not possible in synthetic
forms of rHGH, but if you want more info just run a search in google. rHGH stimulates
growth in most body tissues which is due to an increase in cell number rather than
cell size. This includes muscle tissue as well as internal organs, hence the dreaded
Use of growth hormone by bodybuilders will cause increased muscle size, localized
and overall bodyfat loss, increased protein synthesis, increased glucose output by
the liver, increased insulin resistance and lowered thyroid output. Stored fats will
be used as a primary fuel source, thus the body fat loss.
So is rHGH the wonder drug everyone lusts after? It certainly is beneficial but not
for everyone. You must be willing to take risks to achieve maximum benefits from its
use, as well as substantial financial investment. Do it right the first time or don’t
do it at all! You will achieve faster and greater growth from cycles of steroids than
with GH, though once you reach a plateau, not many products work better.
Ok, so now you have decided that this is the drug for you and you are ready to try
it, so what next? Well here are some general guidelines to follow for maximal results
from GH use:
Daily injections are a must to maintain stable blood levels as GH has a very short
life span in the body. It will peak almost immediately after injection and will clear
the body with a half-life of only 20-30 minutes. It is best injected first thing in
the morning upon rising to raise levels that are very low from sleeping, and immediately
after training. I do not recommend injecting before bed as many bodybuilders do, since
that is the time of day that your body will release naturally high levels of growth
hormone, and exogenous use will only block that release. If you take it in the morning
when levels are low, after training when levels are depleted and then let your body
release while sleeping, you are getting one extra release for free! GH is best taken
long term, short cycles do not maximize the benefits of muscle cell increase, only
fat loss. Here is how I take my GH for maximum benefits:
6iu ed injected sub-q, preferably in the stomach
3iu injected upon rising, 3iu injected immediately post-workout
10iu insulin taken 30 minutes after GH injection
25mcg cytomel ed
use of androgens such as testosterone
The timing of GH and insulin injections is critical. If insulin is injected before
the GH, your pancreas will stop release of insulin monitoring due to the exogenous
source. GH when injected will mobilize stored glycogen release which will turn into
glucose for energy. This will cause a rapid rise in blood sugar levels that will not
shut down or stop rising due to the feedback loop being momentarily cut off. You will
go hyperglycemic and end up in the hospital. You must first inject your GH, then the
insulin; this will cause a rise in glucose release by the GH and will be controlled
and shuttled into muscle tissue for repair by the later injection of insulin.
Use of cytomel or some type of T3 hormone is critical since GH use will severely
lower thyroid levels. Small exogenous sources are necessary to maintain normal levels
and 25 mcg ed is sufficient. This will also aid in body fat loss by maintaining proper
Use of androgens is also necessary due to the promotion of anabolism by increasing
muscle size that benefits the new cell number increase by the GH. Remember GH will
not directly cause muscle cell size increase, just the number of cells, therefore,
androgens are necessary to increase size. Testosterone or trenbolone are both highly
androgenic and perfect for out stack.
One myth that needs to be cleared up: high doses of GH use and the 5 on 2 off program.
First, if you find that you are not achieving results off of 4-6iu ed, than something
else is the problem, not your dose. The use of high doses if primarily cause by heat
damage to the protein chain causing denatured proteins. This will decrease the effect
and you must use higher doses to achieve the same effect. Other reasons for high dose
use are; fake gh, not using insulin, cytomel or test, poor diet, improper timing schedule
and the 5 on 2 off. This program was recommended by dealers as a way to move product
by offering a lower cost cycle. No doctor in the world would recommend this protocol,
Peak blood concentrations are reached in 2-6 hours after injection, and therefore,
multiple daily injections are necessary to achieve stable release schedule and results.
If you take your last injection Friday afternoon, and then not again till Monday morning,
then you have negated all effects offered by the 6 hour concentration. Yes, you will
achieve results using a 5 on 2 off program, but not as well as if you inject ed. It’s
your money; I can only tell you how to optimize use.
Side effects of GH use include; carpal tunnel syndrome, tingling in the extremities,
numbness in the hands and feet, increased organ growth, decreased insulin reception,
acromegaly but only in extreme dose use, and decreased thyroid output causing fat
accumulation. If you find that you are experiencing any of the above side effects,
lower your dose immediately. This is especially important with carpal tunnel. If you
feel like your wrists are hurting then lower the dose until pain subsides. You do
not want to have that surgery, trust me.
GH is a fantastic product, beneficial for many reasons. Most people will experience
thinning of the skin, increased vascularity, fat loss, permanent increases in muscle
size due to the cell number increase, and overall feelings of wellness. You will probably
need less sleep and feel supercharged all day long. I highly recommend GH use, but
only when you have the money to do it right. 4-6 month cycles are optimal, year round
if you are over age 35. If you have anything of benefit to add to this thread, feel
free to contribute or PM me.
This was posted in the "Very Basix Question on T3/ GH" thread by Mr. Vic.
All thanks go to him. But I was wondering if you had any input, especially the final
conclusion at the very end of the artice: "If you’ve been using GH without T4,
you’ve been wasting half your money – and if you’ve been using it with T3, you’ve
been wasting your time. Start using T4 with your GH, and you’ll finally be getting
the full results from your investment."
Thyroid Hormone + Growth Hormone
(IF you aren’t using T4 with your GH, you’re not doing it right)
By Anthony Roberts with James Daemon, PhD.
Quite some time ago, I wrote a book on Anabolics, and since then, I’ve received quite
a bit of feedback on it. Some of the information contained in the book is based on
the 50-60 profiles I completed for Steroid.com’s main page. As a result, I get feedback
on certain portions of the book from people who have read them online.
When someone takes the time to send an e-mail to Steroid.com or AnabolicBooks LLC,
they’re screened, and eventually some of them make their way to my e-mail account.
AnabolicBooks LLC is publisher- a little known fact is that my book is actually wasn’t
edited by me, nor do I own the rights to any of it. When they forward an e-mail to
me, I typically consider it very carefully, and reply to the original sender. If amendments
or additions are useful for anything I’ve previously written (readers frequently send
me recently published studies), I typically reply and thank the person for their help.
This time, something odd happened. I was forwarded an e-mail from AnabolicBooks,
and the reader seemed to know what he was talking about, but (I thought) mistaken
about interactions between Growth Hormone and Thyroid medication. I took a look at
the e-mail, and knew that I could quickly find a study that I had saved previously,
to send to the reader, to verify that the claims in my work on GH were sound.
In this particular case- James Daemon, PhD- was the reader, and was correct in his
assessment of the interaction between thyroid hormone and Growth Hormone. And, in
direct contradiction, so was I. Thyroid medication decreases the anabolic effect of
Growth Hormone. And it increases it.
There’s some leaps here, because research in some of the necessary areas is sketchy
(or not done yet), but if you read the entirety of this article, you’ll learn how
to get a significantly more gains from Growth Hormone, for pennies a day, by the addition
of a readily available (and cheap) addition to it. And yeah, it’s a drug you can get
anywhere on the ‘net, very easily. And no, it’s not a steroid.
In fact, I’ll go so far as to say you’re throwing away a substantial portion of your
gains from growth hormone if you are not using this drug with it.
Ok…I’ll explain things a bit further. First, a brief explanation of Thyroid Hormone
as well as Growth Hormone may be necessary.
Your thyroid gland secretes two hormones that are going to be of primary importance
in understanding Thyroid/ GH interaction. The first is thyroxine (T4) and the second
is triiodothyronine (T3). T3 is frequently considered the physiologically active hormone,
and consequently the one on which most athletes and bodybuilders focus their energies
on. T4, on the other hand, is converted in peripheral tissue into T3 by the enzymes
in the deiodinase group, of which there are three types- the three iodothyronine deiodinase
either catalyze the initiation (D1, D2) or termination (D3) of thyroid hormone effects.
The majority of the body's T3 (about 80%) comes from this conversion via the first
two types of deiodinase, while conversion to an inactive state is accomplished by
the third type.
It’s important to note that not all of the body’s T4 is converted to T3, however-
some remains unconverted. The secretion of T4 is under the control of Thyroid Stimulating
Hormone (TSH) which is produced by the pituitary gland. TSH secretion is in turn controlled
through release of Thyrotropin Releasing Hormone which is produced in your hypothalamus.
So, when T3 levels go up, TSH secretion is suppressed, due to the body’s self regulatory
system known as the “negative feedback loop” . This is also the mechanism whereby
exogenous thyroid hormone suppresses natural thyroid hormone production. However,
it should be noted that thyroid stimulating hormone (like all other hormones) can
not work in a vacuum. TSH also requires the presence of Insulin or Insulin-like Growth
Factor to stimulate thyroid function (1) When thyroid hormone is present without either
insulin or IGF-1, it has no physiological effect (ibid).
Most people think that T3 is just a physiologically active hormone that regulates
bodyfat setpoint and has some minor anabolic effects, but in actuality, in some cases
of delayed growth in children, T3 is actually too low, while GH levels are normal,
and this has a growth limiting effect on several tissues (2) This could be due to
T3’s ability to stimulate the proliferation of IGF-1 mRNA in many tissues (which would,
of course, be anabolic), or it could be due to the synergistic effect T3 has on GH,
specifically on regulation of the growth hormone gene. Although it is largely overlooked
in the world of performance enhancement, regulation of the growth hormone response
is predominantly determined by positive control of growth hormone gene transcription
which is proportional to the concentration of thyroid hormone-receptor complexes,
which are influenced by T3 levels. (3)
At this point, just to give you a better understanding of what’s going on, I think
it’s prudent to also give a brief explanation of Growth Hormone ( GH) as well.
Your body’s GH is regulated by many internal factors, such as hormones and enzymes.
hormones. A change in the level of your body’s GH output begins in the hypothalamus
with somatostatin (SS) and growth hormone-releasing hormone (GHRH). Somatostatin exerts
its effect at the pituitary to decrease GH output, while GHRH acts at the pituitary
to increase GH output. Together these hormones regulate the level of GH you have in
your body. In many cases, GH deficiency presents with a low level of T3, and normal
4). This is of course because conversion of T4-T3 is partially dependant on GH (and
to some degree GH stimulated IGF-1), and it’s ability to stimulate that conversion
process of T4 into T3.
Interestingly, the hypothalamus isn’t the only place where SS is contained; the thyroid
gland also contains Somatostatin-producing cells. This is of interest to us, because
in the case of the thyroid, it’s been noted that certain hormones which were previously
thought only to govern GH secretion can also influence thyroid hormone output as well.
SS can directly act to inhibit TSH secretion or it may act on the hypothalamus to
inhibit TRH secretion. So when you add GH into your body from an outside source, you
are triggering the body into releasing SS, because your body no longer needs to produce
its own supply of GH…and unfortunately, the release of SS can also inhibit TSH, and
therefore limit the amount of T4 your body produces.
But that’s not the only interaction we see between the thyroid and Growth Hormone.
As we learned in high-school Biology class, the body likes to maintain homeostasis,
or “normal” operating conditions. This is the body’s version of the status quo, and
it fights like hell to maintain the comfort of the status quo (much like moderators
on most steroid discussion boards). What we see with thyroid/ GH interplay is that
physiological levels of circulating thyroid hormones are necessary to maintain normal
pituitary GH secretion, due to their directly stimulatory actions. However, when serum
concentrations of thyroid hormone increase above the normal range we see an increase
in hypothalamic somatostatin action, which suppresses pituitary GH secretion and overrides
any stimulatory effects that the thyroid hormone may have had on GH. The suppression
of GH secretion by thyroid hormones is probably mediated at the hypothalamic level
by a decrease in GHRH release(5).
In addition, as IGF-I production is increased in the hypothalamus after T3 administration
and T3 may participate in IGF-1 mediated negative feedback of GH by triggering either
increased somatostatin tone and/or decreased GHRH production (6). IGF, interestingly,
has the ability to mediate some of T3’s effects independent of GH, but not to the
same degree GH can (7.) In fact, IGF-I production is increased in the hypothalamus
after T3, administration it may plausibly participate in negative feedback by triggering
either increased somatostatin tone and/or decreased GHRH production. So we know that
GH lowers T4 (more about this in a sec), but an increase in T3 upregulates GH receptors
(8) as well as IGF-1 receptors (9,10).
As can be previously stated, and due to the ability of GH to convert inactive T4
into active T3, GH administration in healthy athletes shows us an entirely predicatble
increase in mean free T3 (fT3), and a decrease in mean free T4 (fT4) levels.(11)
Interaction between GH, IGF-I, T3, and GC. GH stimulates hepatic IGF-I secretion
and local production of growth plate IGF-I, and exerts direct actions in the growth
plate. Circulating T3 is derived from the thyroid gland and by enzymatic deiodination
of T4 in liver and kidne.. The regulatory 5'-DI and 11ßHSD type 2 enzymes may also
be expressed in chondrocytes to control local supplies of intracellular T3 and GC.
Receptors for each hormone (GHR, IGF-IR, TR, GR) are expressed in growth plate chondrocytes.
So, with the use of GH, what we see is an increased conversion of T4-T3, and possible
inhibition of Thyroid Releasing Hormone by Somatostatin, and therefore even though
T3 levels may rise, there is no increase in T4 (logically, we see a decrease). Now,
as we’ve seen, GH is HIGHLY synergistic with T3 in the body, and as a mater of fact,
if you’ve been paying any attention up until this point, you’ll note that the limiting
factor on GH’s ability to exert many of it’s effects, is mediated by the amount of
T3 in the body.
As noted before, T3 enhances many effects of GH by several mechanisms, including
(but not limited to): increasing IGF-1 levels, IGF-1 mRNA levels, and finally by actually
mediating the control of the growth hormone gene transcription process as seen below:
Comparison of the kinetics of L-T3-receptor binding abundance to changes in the rate
of transcription of the GH gene.(3)
As you can see, T3 levels are directly correlative to GH gene transcription. The
scientists who conducted the study which provided the graph above concluded that the
amount of T3 present is a regulatory factor on how much GH gene transcription actually
occurs. And gene transcription is what actually gives us the effects from GH. This
last fact really seems to shed some light on why we need T3 levels to be supraphysiological
if we’re going to be using supraphysiological levels of GH, right? Otherwise, the
GH we’re using is going to be limited by the amount of T3 our body produces. However,
since we’re taking GH, and it is converting more T4 into T3, T4 levels are lowered
substantially, and this is the problem with GH. and may actually be THE limiting factor
on GH…if we assume that at least some of GH’s effects are enhanced by thyroid hormone,
and specifically T3, then what we are looking at is the GH that has been injected
is being limited by a lack of T3. But that doesn’t make sense, because if we use T3
+ GH, we get a decrease in the anabolic effect of GH.
This is where Mr. Daemon, who had contacted me via an e-mail to my publisher, about
Thyroid + GH interaction, was able to shed some light on things. You see, I knew that
it couldn’t just be the actual presence of enough T3 along with the GH that was limiting
GH’s anabolic effect, because, simply adding T3 to a GH cycle will reduce the anabolic
effect of the GH (12.).
Originally, he had said to me that T3 was synergistic with GH, wheras I said that
T3 actually reduced the anabolic effects of GH- now I realize we were both correct.
Logically this presents a bit of a problem, which I believe can be solved. This came
from reading several studies provided to me by Dr.Daemon. the trend I was seeing was
that even when Growth Hormone therapy was used, T3 levels needed to be elevated in
order to treat several conditions caused by a lack of natural growth hormone. And
even if the patient was on GH, T3 levels still needed to be elevated. And what I noticed
was that those levels were elevated successfully by using supplemental T4 but not
Here’s why I think this is:
Additional T3 is not all that’s needed here. What’s needed is the actual conversion
process of T4-T3, and the deiodinase presence and activity that it involves. This
is because Local 5'-deiodination of l-thyroxine (T4) to active the thyroid hormone
3,3',5-tri-iodothyronine (T3) is catalyzed by the two 5'-deiodinase enzymes (D1 and
D2). These enzymes not only “create” T3 out of T4, but actually regulates various
T(3)-dependent functions in many tissues including the anterior pituitary and liver.
So when there is an excess of T3 in the body, but normal levels of T4, the body’s
thyroid axis sends a negative feedback signal., and produces less (D1 and D2) deiodinase,
but more of the D3 type, which signals the cessation of the T4-T3 conversion process,
and is inhibitory of many of the synergistic effects that T3 has! Remember, Type 3
iodothyronine deiodinase (D3) is the physiologic INACTIVATOR of thyroid hormones and
their effects (13) and is well known to have independent interaction with growth factors
(which is what GH and IGF-1 are).(14) This is because with adequate T4 and excess
T3, (D1 and D2) deiodinase is no longer needed for conversion of T4 into T3, but levels
of D3 deiodinase will be elevated. When there is less of the first two types of deidinase,
it would seem that the T3 which has been converted to T4 can not exert it’s protein
sparing (anabolic effects), as those first two types are responsible for mediation
of many of the effects T3 has on the body. This seems to be one of the ways deiodinase
contributes to anabolism in the presence of other hormones.
All of this would explain why anecdotally we see bodybuilders who use T3 lose a lot
of muscle if they aren’t using anabolics along with it- they’re not utilizing the
enzyme that would regulate some of T3’s ability to stimulate protein synthesis, while
they are simultaneously signaling the body to produce an inhibitory enzyme (D3). And
remember, for decades bodybuilders who were dieting for a contest have been convinced
that you lose less muscle with T4 use, but that it’s less effective for losing fat
when compared with T3? Well, as we’ve seen, without something ( GH in this case) to
aid in the conversion process, it would clearly be less effective! Since the deiodinase
enzyme is also located in the liver, and we see decreased hepatic nitrogen clearance
with GH + T3, it would seem that the D3 enzyme is exerting it’s inhibitory effects,
but in the absence of the effects of the first two deiodinase enzymes, it remains
unchecked and therefore not only limits the GH’s nitrogen retention capability.
In other words, if we have enough to GH in our body aid in supraphysiological conversion
of T4 into T3, but we already have the too much (exogenous) T3, the GH is not going
to be converting any excess T4 into T3 after a certain point- which would be a limiting
factor in GH’s anabolic effects, when coupled with the act that we’ve allowed the
D3 enzyme to inhibit the T3/ GH synergy that is necessary.
As further evidence, when we look at certain types of cellular growth (the cartilage
cell in this case) we see that GH induced rises in IGF-I stimulates proliferation,
whereas T3 is responsible for hypertrophic differentiation. So it would seem that
in some tissues, IGF-1 stimulates the synthesis of new cells, while T3 makes them
larger. In this particular case, The fact that T4 and (D1) deiodinase is am
active component in this system is noted by the authors. They clearly state (paraphrasing)
that: “T4 is is converted to T3 by deiodinase (5'-DI type 1) in peripheral tissues…[furthermore]
conversion of T4 to T3 , suggesting that some effects of GH
may involve this pathway.” The thing I want you to notice is that the authors of
this paper state that the that the conversion PATHWAY is probably involved, and not
the simple presence of T3. (15 )
Also, that same study notes that T3 has the ability to stimulates IGF-I and expression
in tissues that whereas GH has no such effect (ibid).
So what are we doing when we add T3 to GH? We’re effectively shutting down the conversion
pathway that is responsible for some of GH’s effects! And what would we be doing if
we added in T4 instead of T3? You got it- we’d be enhancing the pathway by allowing
the GH we’re using to have more T4 to convert to T3, thus giving us more of an effect
from the GH we’re taking. Adding T4 into our GH cycles will actually allow more of
the GH to be used effectively!
Remember, the thing that catalyzes the conversion process is the deiodinase enzyme.
This is also why using low amounts of T3 would seem (again, anecdotally in bodybuilders)
to be able to slightly increase protein synthesis and have an anabolic effect – they
aren’t using enough to tell the body to stop or slow down production of the deiodinase
enzyme, and hence .Although this analogy isn’t perfect, think of GH as a supercharger
you have attached to your car…if you don’t provide enough fuel for it to burn at it’s
increased output level, you aren’t going to derive the full effects. Thyroid status
also may influence IGF-I expression in tissues other than the liver.So what we have
here is a problem. When we take GH, it lowers T3 levels…but we need T3 to keep our
GH receptor levels optimally upregulated. In addition, it’s suspected that many of
GH’s anabolic effects are engendered as a result of production of IGF-1, so keeping
our IGF receptors upregulated by maintaining adequate levels of T3 seems prudent.
But as we’ve just seen, supplementing T3 with our GH will abolish Growth Hormone’s
functional hepatic nitrogen clearance, possibly through the effect of reducing the
bioavailability of insulin-like growth
So we want elevated T3 levels when we take GH, or we won’t be getting ANYWHERE NEAR
the full anabolic effect of our injectable GH without enough T3. And now we know that
not only do we need the additional T3, but we actually want the CONVERSION process
of T4 into T3 to take place, because it’s the presence of those mediator enzymes that
will allow the T3 to be synergistic with GH, instead of being inhibitory as is seen
when T3 is simply added to a GH cycle. And remember, we don’t only want T3 levels
high, but we want types 1 and 2 deiodinase to get us there- and when we take supplemental
T3, that just doesn’t happen…all that happens is the type 3 deiodinase enzyme shows
up and negates the beneficial effects of the T3 when we combine it with GH.
And that’s where myself and Dr. Daemon ended up, after a week of e-mails, researching
studies, and gathering clues.
If you’ve been using GH without T4, you’ve been wasting half your money – and if
you’ve been using it with T3, you’ve been wasting your time. Start using T4 with your
GH, and you’ll finally be getting the full results from your investment.